Investigator’s Manual for
the Protection of Human Subjects
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Chapter 11: Glossary

11. Glossary

Suggested lay language Translations for informed consent forms

  1. Acute: new, recent, sudden
  2. Adverse Effect: side effect
  3. Assay: lab test
  4. Benign: not malignant or threatening, usually without serious consequence
  5. Bolus: an amount given all at once
  6. Carcinogenic: capable of causing cancer
  7. Catheter: a tube for withdrawing or introducing fluids
  8. Chronic: continuing for a long time
  9. Clinical Trial: an experiment in patients
  10. Controlled Trial: a study in which the experimental treatment procedures are compared to a standard (control) treatment or procedure
  11. Contraindicated should not be used
  12. Culture: test for infection or organisms that could cause infection
  13. Double Blind: a study in which neither the investigators nor the subjects know what drug the subject is receiving
  14. Dysplasia: abnormal cells
  15. Edema: increased fluid
  16. Efficacy: effectiveness
  17. Failed therapy subjects do not "fail therapies" but rather therapies fail to help subjects
  18. Hematoma: a bruise, a black and blue mark
  19. Heparin Lock: a needle placed in the arm with blood thinner to keep the blood from clotting
  20. Monitor: check on; keep track of; watch carefully
  21. Morbidity: undesired result or complication
  22. Mortality: death or death rate
  23. Necrosis: death of tissue
  24. Oncology: the study of tumors or cancer
  25. Percutaneous: through the skin
  26. Placebo: an inactive substance like a sugar pill
  27. PRN: as needed
  28. Protocol: a plan of study
  29. Random: by chance, like the flip of a coin
  30. Relapse: the return of a disease
  31. Retrospective Study: a study looking back over past experience

 


Investigator’s Manual for
the Protection of Human Subjects
Table of Contents
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Chapter 11: Glossary
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October 29, 2004
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