• CONTACT HRPP
• Program Feedback
• IRB Staff
• Campus Consults



• WHAT'S NEW
• Human Research News



• FOR RESEARCHERS
• Meeting Calendars
• IRB Descriptions
• Forms
• Policies & Guidance
• Investigator Survey
• Other Resources
• Participants' Bill of Rights
• Certification, Education and Training



• FOR AND ABOUT IRB MEMBERS
• Meeting Calendars
• IRB Member rosters
• Checklists for Members



• FOR RESEARCH PARTICIPANTS
• Información Para Participantes
• Participant Survey



• ABOUT UCLA IRBS
• Federalwide Assurance
• Human Research Policy Board

7. Responsibilities of Principal Investigators

Investigators should be aware of certain, specific responsibilities that are undertaken when conducting research. Although most investigators are familiar with some of the paperwork requirements associated with research, there are many reporting requirements which are often overlooked by investigators until problems are encountered with respect to a certain research activity. In today’s litigious environment, it is important for investigators to prepare and maintain clear documentation of research activities in an attempt to minimize or alleviate unnecessary confusion which may arise during the performance of research and during the course of routine audits carried out by the HSPC, Data Safety Monitoring Board or other sponsoring or regulatory bodies.

Application and Definitions

Investigators are required to obtain a prospective UCLA HSPC review and approval if any of the following criteria exist:

1. When research with human subjects is conducted by or under the direction of any employee, student or agent of UCLA in connection with his or her institutional responsibilities, or
2. When the conduct or recruitment of the research involves institutional resources (property, facilities or funding, including extramural funds administered by UCLA), or
3. When the research involves the use of UCLA’s non-public information to identify or contact human research subjects or prospective subjects.
4. Investigators who transfer research to UCLA from their previous institution are required to submit the project to the HSPCs for review and approval in order to continue the study.